The prosthetic treatment plan must allow an ideal integration of esthetics, biologics and functional requirements on natural teeth and on implants. In case of implants the prosthetic treatment is usually more challenging due to the inevitable soft tissues changing after teeth extraction. In fact, the soft-tissue healing and management around implants represents a crucial aspect and must be considered also from a prosthetic point of view in order to conclude the therapy with excellent outcomes. In this sense the prosthetic components assume an essential role in order to idealize the prosthetic integration and simultaneously achieve reliable and stable prosthetic results. Clinical situations require specific evaluations in terms of implant connection, prosthetic components and restorative materials and approaches. Nowadays, it is well known that the biological integration and stability around implants, can be significantly influenced by the correct use of modern prosthetic components. In this sense the use of not-removable prosthetic components allows to idealize the bone and soft tissues healing and management around implant with significant advantage from a biological, biomechanical and clinical point of views. With this approaches nowadays it is possible to idealize the bone and soft tissue integration around dental implants, reducing or avoiding the marginal bone remodeling and in the same time obtaining and ideal soft tissues healing. The On1 concept offers an undisturbed mucosal seal with many advantages for both surgeons and restorative clinicians. It provides surgical flexibility along with soft tissue biocompatibility, but also provides a simplified restorative workflow. A sufficient volume of healthy bone is another one of the prerequisites for achieving a predictable long term function and esthetic result of endosseous implants. In particular in the treatments of the esthetics areas the preservation or the augmentation of the bone volume is crucial in order to achieve excellent prosthetic outcomes. In fact, both in case of immediate implant placements and delayed approaches, the possibility to preserve or recreate respectively a correct natural architecture, is an indispensible aspect to consider in the treatment plan. In this sense the chance to use a biocompatible biomaterials as framework for bone formation, allows to simplify to management of this clinical situations achieving an adequate and stable bone volume. In fact this material acts as a slowly resorbing scaffold for regenerative processes and maintains space for bone regeneration.